The operating system for quantitative clinical pharmacology
Agentic AI for drug development
Zynthari handles the data, QC and infrastructure, so you can spend your time on the science.
MVP Alpha design preview · synthetic studies. Data review, the knowledge graph and QC release are still being built.
The problem
Most PMX consultancies are one or two people. Most of their week goes to files, datasets and QC. The science gets what's left.
What Zynthari takes on
- Analysis-ready datasets
- A standard workflow for every analysis
- QC and version control on every script
- A workspace for each client, in our cloud or your client's
Who does what
You keep
- Your clients
- Your science
- Your sign-off
Zynthari runs
- The datasets
- QC and version control
- The infrastructure
Find the data problems before your client does.
Drop in a sponsor's study files. Zynthari checks them against the protocol and builds the analysis-ready dataset.
| Subject | Time (h) | Conc | Unit | Dose (mg) | Infusion (h) |
|---|---|---|---|---|---|
| 101-011 | 0 | BLQ | ug/mL | 887 | 1.0 |
| 101-011 | 1 | 231.4 | ug/mL | 887 | 1.0 |
| 101-011 | 24 | 162.0 | ug/mL | 887 | 1.0 |
| 101-014 | 1 | 228500 | ng/mL1 | 912 | 1.0 |
| 101-014 | 24 | 158900 | ng/mL1 | 912 | 1.0 |
| 101-017 | 1 | 240.2 | ug/mL | 905 | 0.52 |
| 101-019 | 1344 | 0.043 | ug/mL | 874 | 1.0 |
Three problems are hiding in this file. Can you spot them?
- Subject 101-014 is in ng/mL. Every other subject is in µg/mL.Protocol p. 31 · bioanalysis in µg/mLConverted to µg/mL, with the change logged.
- Subject 101-017's infusion ran 0.5 h. The protocol sets 1 hour.Protocol p. 12 · Part A dosingSent to you to confirm with the site.
- 0.04 µg/mL at 1344 h is below the 0.1 µg/mL limit.Protocol p. 31 · LLOQFlagged BLQ and handled by your analysis plan's rule.
| USUBJID | ATPTN | AVAL | AVALU | BLQ | Note |
|---|---|---|---|---|---|
| ABX-101-011 | 0 | 0 | ug/mL | 1 | |
| ABX-101-011 | 1 | 231.4 | ug/mL | 0 | |
| ABX-101-011 | 24 | 162.0 | ug/mL | 0 | |
| ABX-101-014 | 1 | 228.5 | ug/mL | 0 | 1 converted |
| ABX-101-014 | 24 | 158.9 | ug/mL | 0 | 1 converted |
| ABX-101-017 | 1 | 240.2 | ug/mL | 0 | 2 query open |
| ABX-101-019 | 1344 | 0 | ug/mL | 1 | 3 BLQ |
Analysis-ready · 7 records · every change logged with its reason
Illustrative example on the synthetic study ABX-101. Data checks are in pilot; checks against the protocol are on the roadmap.
Then run the analysis in Studio.
Click through one study in the demo: data mapping, NCA and a population PK model, on synthetic data.
Pilot Zynthari on one study.
- Consultants
- Apply for the partner pilot.
- Sponsors
- Tell us what you need and we'll connect you with a partner.
Or email intakezynthari@gmail.com.
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